CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 75 enrolled
Drug / intervention
Lansoprazole Tablet +4 moredrug
Likely dose
Lansoprazole Tablet 40 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00335283
NCT00335283Phase 3Completed

Randomized Placebo-Controlled Trial of BID Lansoprazole in Isolated Chronic Post Nasal Drip

Vanderbilt University·interventional·Posted Jun 9, 2006·Updated Aug 21, 2012

In Brief

A Phase 3 clinical trial evaluating Lansoprazole Tablet, PH and impedence testing, and 3 other interventions for Larynx Disease. Completed, enrolled 75 participants across 1 site.

Detailed Summary

The purpose of this study is to determine whether aggressive acid suppression with Lansoprazole is effective in the treatment of post nasal drip, and also assess the predictors of response based on clinical and physiologic parameters.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsLarynx Disease
CountriesUnited States

Timeline

Phase 3CompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJun 9, 2006
Enrollment StartAug 1, 2006
Primary CompletionDec 1, 2008
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 20.1 years ago

Interventions

Lansoprazole Tabletdrug

40 mg bid x 16 weeks

PH and impedence testingprocedure

24 hour ph monitoring

manometryprocedure

done prior to pH probe to measure length of esophagus

lansoprazoledrug

40mg bid

placebodrug

one tablet bid