CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 41 enrolled
Drug / intervention
palonosetron hydrochloride +8 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00343863
NCT00343863N/ACompleted
CompareCT.gov

Efficacy of Palonosetron in the Prevention of Acute and Delayed Chemotherapy-Induced Nausea and Vomiting Following Dose Dense Adriamycin-Cyclophosphamide Chemotherapy in Early Stage Breast Cancer Patients

University of Washington·interventional·Posted Jun 23, 2006·Updated Jul 11, 2017

In Brief

A clinical study evaluating palonosetron hydrochloride, cyclophosphamide, and 7 other interventions for Male Breast Cancer and 4 related conditions. Completed, enrolled 41 participants across 1 site.

Detailed Summary

RATIONALE: Antiemetic drugs, such as dexamethasone, ondansetron hydrochloride, and palonosetron hydrochloride, may help lessen or prevent nausea and vomiting caused by chemotherapy. PURPOSE: This clinical trial studies how well giving dexamethasone together with ondansetron hydrochloride or palonosetron hydrochloride works in preventing nausea and vomiting in patients receiving doxorubicin hydrochloride and cyclophosphamide for early stage breast cancer

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMale Breast Cancer, Nausea and Vomiting, Stage I Breast Cancer, Stage II Breast Cancer, Stage IIIA Breast Cancer
CountriesUnited States
CollaboratorsNational Cancer Institute (NCI)

Timeline

N/ACompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJun 23, 2006
Enrollment StartJan 1, 2006
Primary CompletionDec 1, 2010
TodayJul 2, 2026
Enrollment to primary: 4.9 yearsPosted 20.0 years ago

Interventions

palonosetron hydrochloridedrug

Given IV

cyclophosphamidedrug

Given orally

dexamethasonedrug

Given orally or IV

doxorubicin hydrochloridedrug

Given IV

quality-of-life assessmentprocedure

Ancillary studies

nausea and vomiting therapyprocedure

Given IV

management of therapy complicationsprocedure

Given IV

ondansetron hydrochloridedrug

Given IV

survey administrationother

Ancillary studies