At a glance
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Assessment of Fibrin Glue in Pterygium Surgery and Other Forms of Ocular Surface Reconstruction
In Brief
A Phase 1 clinical trial evaluating Tisseel fibrin adhesive for Pterygium and Ocular Surface Cicatrizing Diseases. Completed, enrolled 32 participants across 1 site.
Detailed Summary
Tisseel fibrin adhesive has been used extensively in many forms of surgery. Its use in eye surgery has been relatively recent. A few studies recently showed it was effective in securing conjunctival grafts in pterygium surgery, and in securing wounds after glaucoma and squint surgery. We sought to confirm its effectiveness in pterygium surgery, as well as prove its effectiveness in securing other material to the ocular surface such as amniotic membrane. Our hypothesis is that fibrin adhesive is effective in securing various types of material to the ocular surface for a sufficient length of time to allow adequate healing before it is absorbed and degraded.
Study Details
Timeline
Interventions
Intraoperative application to scleral bed and graft