CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 4,432 enrolled
Drug / intervention
GSK Biologicals' Haemophilus influenzae type b and Neisseria meningitidis serogroups C and Y-tetanus toxoid conjugate vaccine combined 792014 +2 morebiological
Likely dose
Not stated in record
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Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00345579
NCT00345579Phase 3Completed

A Single-blind, Randomized, Controlled, Multinational Study for the Evaluation of Safety of GlaxoSmithKline (GSK) Biologicals' Investigational Vaccination Regimen Compared to Monovalent Haemophilus Influenzae Type b (Hib) Control Vaccine in Healthy Infants at 2, 4, 6, and 12 to 15 Months of Age.

GlaxoSmithKline·interventional·Posted Jun 28, 2006·Updated Dec 16, 2016

In Brief

A Phase 3 clinical trial evaluating GSK Biologicals' Haemophilus influenzae type b and Neisseria meningitidis serogroups C and Y-tetanus toxoid conjugate vaccine combined 792014, ActHIB, and 1 other intervention for Haemophilus Influenzae Type b and Neisseria Meningitidis. Completed, enrolled 4,432 participants across 63 sites in 2 countries.

Detailed Summary

The primary phase of this study is evaluating the safety of Hib-MenCY-TT vaccine compared to a control group receiving licensed Hib conjugate vaccine, when each are co-administered with Pediarix® to healthy infants at 2, 4, and 6 months of age. This protocol posting deals with objectives \& outcome measures of the primary phase of the study. The objectives \& outcome measures of the Booster phase are presented in a separate protocol posting (NCT number = 00345683). The Protocol Posting has been updated in order to comply with the FDA Amendment Act, Sep 2007

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesMexico, United States
Collaborators--

Timeline

Phase 3CompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJun 28, 2006
Enrollment StartSep 1, 2006
Primary CompletionOct 1, 2007
Study CompletionMar 1, 2008
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 20.0 years ago

Interventions

GSK Biologicals' Haemophilus influenzae type b and Neisseria meningitidis serogroups C and Y-tetanus toxoid conjugate vaccine combined 792014biological

3-dose intramuscular injection

ActHIBbiological

3-dose intramuscular injection

Pediarix/Infanrix Pentabiological

3-dose intramuscular injection