CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 2,337 enrolled
Drug / intervention
Boostrix™ +1 morebiological
Likely dose
Not stated in record
Key inclusion· 2
  • Healthy male or female
  • Age 19 to 64 years at study vaccination
Key exclusion· 6
  • Any prior Tdap vaccine administration
  • Td booster within previous 5 years
  • Investigational or non-registered product (drug or vaccine) within 30 days before study vaccine
  • Chronic immunosuppressants or use within 6 months before study vaccine

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00346073
NCT00346073Phase 3Completed

A Study to Evaluate Immunogenicity and Safety of Boostrix Compared to Adacel When Administered as a Booster Vaccination in Adults Aged 19 to 64 Years of Age

GlaxoSmithKline·interventional·Posted Jun 29, 2006·Updated Aug 7, 2018

In Brief

A Phase 3 clinical trial evaluating Boostrix™ and ADACEL® for Acellular Pertussis and 2 related conditions. Completed, enrolled 2,337 participants across 42 sites.

Detailed Summary

GSK Biologicals' dTpa vaccine has recently been approved by the US Food and Drug Administration (FDA) for booster vaccination of adolescents aged 10 to 18 years. The ACIP has recently issued provisional recommendations for universal adult Tdap vaccination. The current study will provide pivotal data in support of extending the age range for Boostrix vaccine to include adults 19-64 years of age.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJun 29, 2006
Enrollment StartJul 13, 2006
Primary CompletionMar 1, 2007
Study CompletionMar 7, 2007
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 20.0 years ago

Interventions

Boostrix™biological

Combined Reduced Antigen Content Diphtheria, Tetanus, Acellular Pertussis Vaccine

ADACEL®biological

Sanofi Pasteur