At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Randomized, Placebo-controlled Trial of St.John's Wort(a Natural Health Product) in the Treatment on Raynaud's Phenomenon
In Brief
A Phase 3 clinical trial evaluating St. John's Wort and Lactose for Raynaud's Disease. Completed, enrolled 20 participants across 1 site.
Detailed Summary
This trial will test the efficacy of St. John's Wort (SJW) as a supplement, in the treatment of Raynaud's phenomenon (RP). The investigators are hypothesizing that taking SJW 300mg, 3 times a day will decrease the frequency, duration, and severity of RP attacks when compared to placebo. Patients with RP will answer questionnaires and self-evaluate their symptoms of RP as a baseline. Then they will be assigned to either a treatment (will receive SJW capsules) or placebo (will receive non-therapeutic capsules) group. They will be required to take their capsules, self-evaluate their progress and be evaluated every two weeks in a clinic. The treatment phase will last six weeks. This trial will be conducted in a way to mimic the normal usage of natural products. Patients will not be required to stop any current treatment for RP.
Study Details
Timeline
Interventions
SJW in capsule form 300 mg PO TID
lactose in gelatin capsule that same as St. John's wort