CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 196 enrolled
Drug / intervention
Placebo +2 moredrug
Likely dose
Placebo 980 milligramfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00361374
NCT00361374Phase 3Completed

Omega-3 Fatty Acids for Treatment of Major Depression: Differential Effects of EPA and DHA, and Associated Biochemical and Immune Parameters

Massachusetts General Hospital·interventional·Posted Aug 8, 2006·Updated Jul 18, 2014

In Brief

A Phase 3 clinical trial evaluating eicosapentaenoic acid, docosahexaenoic acid, and 1 other intervention for Major Depressive Disorder. Completed, enrolled 196 participants across 1 site.

Detailed Summary

This study examines the difference in the effectiveness of two natural compounds, eicosapentanoic (EPA) and docosahexanoic (DHA)omega-3 fatty acids, in treating major depressive disorder. Both types of omega-3 fatty acids are commonly found in fish oils. It is believed that a deficiency in these omega-3 fatty acids may lead to the development of major depression.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 3CompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedAug 8, 2006
Enrollment StartJul 1, 2006
Primary CompletionFeb 1, 2013
Study CompletionMar 1, 2013
TodayJul 2, 2026
Enrollment to primary: 6.6 yearsPosted 19.9 years ago

Interventions

eicosapentaenoic aciddietary

1 gram/day

docosahexaenoic aciddietary

1 gram/day

Placebodrug

980 milligram/day