CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 16 enrolled
Drug / intervention
Vorinostat +1 moredrug
Likely dose
Vorinostat 600 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00373490
NCT00373490Phase 1Completed

MK0683 Phase1 Clinical Study - Solid Tumor -

Merck Sharp & Dohme LLC·interventional·Posted Sep 8, 2006·Updated Aug 27, 2015

In Brief

A Phase 1 clinical trial evaluating Vorinostat for Tumors. Completed, enrolled 16 participants.

Detailed Summary

This is a clinical study to evaluate the safety and pharmacokinetics of an overseas determined maximum tolerated dose (MTD) of MK-0683 (vorinostat) in a Japanese patient population with solid tumors.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTumors
Countries--
Collaborators--

Timeline

Phase 1CompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 8, 2006
Enrollment StartJul 1, 2006
Primary CompletionOct 1, 2007
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 19.8 years ago

Interventions

Vorinostatdrug

600 mg daily (300 mg twice daily \[b.i.d.\]) for 3 consecutive days followed by 4 days of rest.

Vorinostatdrug

400 mg once daily (400 mg q.d.) continuous daily dosing for 21 days.