CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed
Drug / intervention
Metformin on top of intensive insulin therapydrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00375388
NCT00375388Phase 3Completed
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Study of Metformin HCL in Patients With Type 2 Diabetes Intensively Treated With Insulin: a Treatment Strategy for Insulin Resistance in Type 2 Diabetes Mellitus: a Randomized Controlled Trial

Bethesda General Hospital, Hoogeveen·interventional·Posted Sep 13, 2006·Updated Sep 13, 2006

In Brief

A Phase 3 clinical trial evaluating Metformin on top of intensive insulin therapy for Type 2 Diabetes Mellitus. Completed, across 1 site.

Detailed Summary

The HOME-trial is a prospective, randomized controlled trial. The purpose of this study is to investigate the effects of metformin HCL in patients with type 2 diabetes mellitus intensively treated with insulin on the quality of the metabolic control of diabetes, the daily dose of insulin, the lipid profile, the blood pressure, the incidence / progression of microvascular and macrovascular complications, and on the qualify of life (Diabetes Health Profile). Early results had been published in Diabetes Care, December 2002, pages 2133-2140.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsType 2 Diabetes Mellitus
CountriesNetherlands
CollaboratorsTakeda, LifeScan, Merck KGaA, Darmstadt, Germany, Dupont Merck, Merck Sharp & Dohme LLC, Novo Nordisk A/S

Timeline

Phase 3CompletedFinished
199819992000200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 13, 2006
Enrollment StartJan 1, 1998
Study CompletionOct 1, 2002
TodayJul 2, 2026
Posted 19.8 years ago

Interventions

Metformin on top of intensive insulin therapydrug