At a glance
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Imaging the Neurobiology of a Behavioral Treatment for Cocaine Dependence
In Brief
A clinical study evaluating Community Reinforcement Approach for Cocaine Dependence. Completed, enrolled 50 participants across 1 site.
Detailed Summary
The purpose of this study is to determine whether patients with the greatest loss of dopamine transmission due to cocaine dependence at pre-treatment PET and MRI scans will be those who fail to respond to substance abuse treatment. This study will also determine whether patients who do respond to treatment will experience a recovery of dopamine function. This study includes free brain imaging and behavioral intervention. Compensation provided for the brain scans.
Study Details
Timeline
Interventions
Community Reinforcement Approach (CRA): The community reinforcement treatment program will be carried out in accordance with NIDA's therapy manual (13).During weeks 13 through 24, patients will meet once per week with their therapists. Sessions will focus on promoting continued change in the life areas addressed in the first 12 weeks of treatment or new components are added as needed.