CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 454 enrolled
Drug / intervention
Diet +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00381290
NCT00381290N/ACompleted
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Intensive Diet and Exercise for Arthritis

Wake Forest University·interventional·Posted Sep 27, 2006·Updated Nov 6, 2017

In Brief

A clinical study evaluating Diet and Exercise for Osteoarthritis. Completed, enrolled 454 participants across 1 site.

Detailed Summary

The purpose of this study is to compare the effects of a calorie-restricting diet, exercise, and a combination of both in reducing knee inflammation and compressive forces in obese and overweight adults with knee osteoarthritis (OA).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOsteoarthritis
CountriesUnited States
CollaboratorsNational Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), General Nutrition Center, Inc

Timeline

N/ACompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 27, 2006
Enrollment StartOct 1, 2006
Primary CompletionJun 1, 2011
TodayJul 2, 2026
Enrollment to primary: 4.7 yearsPosted 19.8 years ago

Interventions

Dietbehavioral

The prescribed diet will include traditional healthy food and up to two meal replacement supplements. Initially, the diet will be set to result in an overall loss of 800 to 1000 calories per day.

Exercisebehavioral

The program will consist of 60-minute exercise sessions per week for the duration of the study. The exercise sessions will incorporate aerobic exercise and resistance training. Participants will also be encouraged to exercise at home.