CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 59 enrolled
Drug / intervention
epithelial cells and blood lymphocyte extractionprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00381628
NCT00381628N/ACompleted
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Use of Nasal Epithelial Cells and Blood Lymphocytes to Identify Markers for Cystic Fibrosis and Cystic Fibrosis Pulmonary Exacerbations

University Hospitals Cleveland Medical Center·observational·Posted Sep 28, 2006·Updated Feb 15, 2019

In Brief

An observational study evaluating epithelial cells and blood lymphocyte extraction for Cystic Fibrosis. Completed, enrolled 59 participants across 1 site.

Detailed Summary

Study Hypothesis: We hypothesize that cellular markers from nasal epithelial cells and blood lymphocytes can serve as potential biomarkers reflect the underlying inflammatory state of the lung and will be helpful in determining the presence of a CF pulmonary exacerbation and its overall severity.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsCystic Fibrosis
CountriesUnited States
CollaboratorsCystic Fibrosis Foundation

Timeline

N/ACompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 28, 2006
Enrollment StartSep 1, 2006
Primary CompletionSep 1, 2011
TodayJul 2, 2026
Enrollment to primary: 5 yearsPosted 19.8 years ago

Interventions

epithelial cells and blood lymphocyte extractionprocedure

Nasal curettage will be performed from each nostril to obtain nasal epithelial cells. Venipuncture will be performed and up to 60-ml of blood will be obtained from which neutrophils will be isolated.