CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 64 enrolled
Drug / intervention
motexafin gadolinium +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00387790
NCT00387790Phase 2Completed

A Phase II Study of Motexafin-Gadolinium (NSC 695238, IND #55583) and Involved Field Radiation Therapy for Intrinsic Pontine Glioma of Childhood

National Cancer Institute (NCI)·interventional·Posted Oct 13, 2006·Updated Jan 4, 2018

In Brief

A Phase 2 clinical trial evaluating motexafin gadolinium and 3-dimensional conformal radiation therapy for Untreated Childhood Brain Stem Glioma. Completed, enrolled 64 participants across 1 site.

Detailed Summary

This phase II trial is studying how well giving motexafin gadolinium together with radiation therapy works in treating young patients with pontine glioma. Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs, such as motexafin gadolinium, may make tumor cells more sensitive to radiation therapy. Giving motexafin gadolinium together with radiation therapy may kill more tumor cells.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedOct 13, 2006
Enrollment StartJun 1, 2007
Primary CompletionApr 1, 2010
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 19.7 years ago

Interventions

motexafin gadoliniumdrug

Given IV

3-dimensional conformal radiation therapyradiation

Undergo focal cranial radiotherapy