At a glance
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Study of the Use of Mild Hypothermia in Out-of-hospital Cardiac Arrest Using a Rapid Infusion of 2 Liters of Cold Normal Saline
In Brief
A Phase 3 clinical trial evaluating Rapid infusion of 2 liters of 4oC normal saline and Rapid infusion of cold normal saline for Out-of-hospital Cardiac Arrest. Completed, enrolled 1,359 participants across 1 site.
Detailed Summary
The overall goal of this study is to determine whether initiating hypothermia in cardiac arrest patients as soon as possible in the field results in a greater proportion of patients who survive to hospital discharge compared to standard prehospital/field care.
Study Details
Timeline
Interventions
Patients randomized to mild hypothermia will receive a rapid infusion of 2 liters of 4oC normal saline prior to arrival in the emergency room. Patients randomized to control will receive standard of care following resuscitation from cardiac arrest.