At a glance
ClinicalIndex Comparison RecordPhase 4Completed· 252 enrolled
Drug / intervention
Captopril +15 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Randomised, Single Blind, Multicentre, 9-month, Phase IV Study, Comparing Treatment Guided by Clinical Symptoms and Signs and NT-proBNP vs Treatment Guided by Clinical Symptoms and Signs Alone, in Patients With Heart Failure (HF) and Left Ventricular Systolic Dysfunction
In Brief
A Phase 4 clinical trial evaluating Captopril, Enalapril, and 14 other interventions for Heart Failure and Ventricular Dysfunction, Left. Completed, enrolled 252 participants across 39 sites.
Detailed Summary
The purpose is to study if HF treatment guided by NTproBNP in addition to clinical symptoms and signs is more effective than treatment guided by clinical symptoms and signs alone in patients with HF and left ventricular systolic dysfunction
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHeart Failure, Ventricular Dysfunction, Left
CountriesSweden
Collaborators--
Timeline
Phase 4CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartOct 2006
First PostedOct 2006
Primary CompletionJan 2009
TodayJul 2026
First PostedOct 25, 2006
Enrollment StartOct 1, 2006
Primary CompletionJan 1, 2009
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 19.7 years ago
Interventions
Captoprildrug
Enalaprildrug
Lisinoprildrug
Ramiprildrug
Trandolaprildrug
Bisoprololdrug
Carvediloldrug
Metoprolol succinatedrug
Candesartandrug
Valsartandrug
Eplerenonedrug
Spironolactonedrug
Diureticsdrug
HF treatment according to Swedish guidelinesdrug
Blood samplesprocedure
The Kansas City Cardiomyopathy Questionnaire (KCCQ)procedure