CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 40 enrolled
Drug / intervention
Essential amino acid supplement +2 moredrug
Likely dose
Essential amino acid supplement 15gfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00393848
NCT00393848Phase 2Completed
CompareCT.gov

Restoration of Muscle Following Hip Surgery

University of Arkansas·interventional·Posted Oct 30, 2006·Updated Jun 2, 2014

In Brief

A Phase 2 clinical trial evaluating Essential amino acid supplement, Ketoconazole, and 1 other intervention for Hip Fracture and 2 related conditions. Completed, enrolled 40 participants across 1 site.

Detailed Summary

The purpose of this study is to determine the effects of two postoperative interventions designed to preserve muscle protein after major hip or knee surgery.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHip Fracture, Osteoarthritis, Femur Head Necrosis
CountriesUnited States
CollaboratorsNational Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Timeline

Phase 2CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedOct 30, 2006
Enrollment StartOct 1, 2006
Primary CompletionOct 1, 2012
TodayJul 2, 2026
Enrollment to primary: 6 yearsPosted 19.7 years ago

Interventions

Essential amino acid supplementdrug

15g of essential amino acid in capsule form three times daily during hospitalization, continued through 6 weeks after discharge.

Ketoconazoledrug

200mg ketoconazole twice daily; started night before surgery and continued through hospitalization.

Placebodrug

Placebo for Ketoconazole