CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 83 enrolled
Drug / intervention
Gadobutrol (Gadavist, Gadovist, BAY86-4875) +1 moredrug
Likely dose
Gadobutrol (Gadavist, Gadovist, BAY86-4875) 0.2 mLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00395733
NCT00395733Phase 3Completed

A Single-blind, Intra-individual, Crossover, Multicenter Study of the Efficacy, Safety and Tolerability of Gadavist (1.0 M) in Comparison With Magnevist (0.5 M) as Contrast Agent in the Enhanced Magnetic Resonance Angiography (MRA) in Chinese Patients

Bayer·interventional·Posted Nov 3, 2006·Updated Dec 18, 2013

In Brief

A Phase 3 clinical trial evaluating Gadobutrol (Gadavist, Gadovist, BAY86-4875) and Gadopentate dimeglumine (Magnevist, BAY86-4882) for Vascular Diseases. Completed, enrolled 83 participants across 3 sites.

Detailed Summary

The purpose of this study is to determine if the contrast agent is effective and safe in the Magnetic Resonance Imaging (MRI) of vascular diseases in patients of Chinese origin.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

Phase 3CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedNov 3, 2006
Enrollment StartOct 1, 2006
Primary CompletionOct 1, 2007
TodayJul 2, 2026
Enrollment to primary: 1 yearPosted 19.7 years ago

Interventions

Gadobutrol (Gadavist, Gadovist, BAY86-4875)drug

Participant received a single intravenous injection with Gadobutrol (1.0 M) at a volume of 0.2 mL/kg BW (dose = 0.2 mmol/kg BW) or up to 0.3 mL/kg BW when 3 Fields of View were imaged (up to dose = 0.3 mmol/kg BW)

Gadopentate dimeglumine (Magnevist, BAY86-4882)drug

Participant received a single intravenous injection with Gadopentate (0.5 M) at a volume of 0.4 mL/kg BW (dose = 0.2 mmol/kg BW) or up to 0.6 mL/kg BW when 3 Fields of View were imaged (up to dose = 0.3 mmol/kg BW)