At a glance
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Strategies for the Treatment of HIV Associated Metabolic Syndrome
In Brief
A clinical study evaluating Metformin, Placebo, and 1 other intervention for HIV Infections and Metabolic Syndrome X. Completed, enrolled 50 participants across 1 site.
Detailed Summary
A healthy diet and exercise have improved the health of people without human immunodeficiency virus (HIV) who have Metabolic Syndrome. In this study we would like to find out if the same benefit can be seen in people with HIV and Metabolic Syndrome. Patients with Metabolic Syndrome usually have a large waist, high blood cholesterol levels, high blood pressure, and high blood sugar levels. These are risk factors, which may increase one's chance of developing heart disease and/or diabetes. The purpose of the study is to evaluate the effects of different methods of treating HIV associated Metabolic Syndrome. The groups are: 1) a lifestyle modification program plus metformin (also known as glucophage), 2) lifestyle modification plus placebo, 3) metformin alone or 4) placebo alone. The lifestyle modification program consists of nutrition and exercise sessions with the goal of improving body composition, heart health, and ways to lower the risk of developing diabetes.
Study Details
Timeline
Interventions
Starting at 500 mg twice daily and increasing to 850 mg twice daily after 3 Months
500 mg twice daily increasing to 850 mg twice daily after 3 Months
Lifestyle Modification