At a glance
ClinicalIndex Comparison RecordN/ACompleted· 17 enrolled
Drug / intervention
Losartandrug
Likely dose
Losartan 100mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Treating the Endothelium to Restore Insulin Sensitivity
In Brief
A clinical study evaluating Losartan for Obesity and 3 related conditions. Completed, enrolled 17 participants across 1 site.
Detailed Summary
A study of 12 weeks' treatment with losartan or placebo, to test the hypothesis that RAS inhibition will improve insulin' vascular actions and therefore improve insulin sensitivity in skeletal muscle.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsObesity, Insulin Resistance, Impaired Glucose Tolerance, Pre-diabetes
CountriesUnited States
Collaborators--
Timeline
N/ACompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartJun 2005
First PostedNov 2006
Primary CompletionNov 2011
Study CompletionMar 2012
TodayJul 2026
First PostedNov 22, 2006
Enrollment StartJun 1, 2005
Primary CompletionNov 1, 2011
Study CompletionMar 1, 2012
TodayJul 2, 2026
Enrollment to primary: 6.4 yearsPosted 19.6 years ago
Interventions
Losartandrug
Tablet, 100mg, once per day for 3 months