At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 310 enrolled
Drug / intervention
linaclotide acetate +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Randomized, Multicenter, Double-blind, Placebo-controlled, Dose-range-finding, Parallel-group, Phase 2 Trial of Oral Linaclotide Acetate Administered to Patients With Chronic Constipation
In Brief
A Phase 2 clinical trial evaluating linaclotide acetate and Matching placebo for Chronic Constipation. Completed, enrolled 310 participants across 60 sites.
Detailed Summary
The primary purpose of this study is to evaluate the efficacy and safety of administration of linaclotide acetate in patients with chronic constipation.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsChronic Constipation
CountriesUnited States
Collaborators--
Timeline
Phase 2CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartNov 2006
First PostedNov 2006
Primary CompletionDec 2007
Study CompletionFeb 2008
TodayJul 2026
First PostedNov 22, 2006
Enrollment StartNov 1, 2006
Primary CompletionDec 1, 2007
Study CompletionFeb 1, 2008
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 19.6 years ago
Interventions
linaclotide acetatedrug
oral, once daily.
Matching placebodrug
oral, once daily