CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 50 enrolled
Drug / intervention
Indacaterol 150 μg +2 moredrug
Likely dose
Indacaterol 150 µg, 300 µg, or 600 µg via single-dose dry powder inhalerAI-extracted
Key inclusion· 3
  • Japanese patients aged 40 to 75 years
  • Moderate to severe COPD
  • Smoking history of at least 20 pack years
Key exclusion· 8
  • Hospitalization for COPD exacerbation within past 6 months
  • Use of long-term oxygen therapy
  • History of asthma
  • Respiratory tract infection within past 1 month

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00403845
NCT00403845Phase 2Completed

A Randomized, Double-blind, Placebo-controlled, 4-period 4-treatment Crossover, Multicenter, Dose-ranging Study to Assess the Efficacy and Safety of 3 Doses of Indacaterol (150, 300, and 600 µg) Delivered Via a Single Dose Dry Powder Inhaler in Japanese Patients With Chronic Obstructive Pulmonary Disease (COPD)

Novartis·interventional·Posted Nov 27, 2006·Updated Aug 17, 2011

In Brief

A Phase 2 clinical trial evaluating Indacaterol 150 μg, Indacaterol 300 μg, and 1 other intervention for Chronic Obstructive Pulmonary Disease. Completed, enrolled 50 participants across 8 sites.

Detailed Summary

The study was designed to obtain data about the efficacy and safety of 3 doses of indacaterol (150, 300, and 600 µg) in Japanese patients with chronic obstructive pulmonary disease (COPD) so that optimal dose(s) could be chosen for testing in later studies.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesJapan
Collaborators--

Timeline

Phase 2CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedNov 27, 2006
Enrollment StartDec 1, 2006
Primary CompletionOct 1, 2007
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 19.6 years ago

Interventions

Indacaterol 150 μgdrug

Indacaterol 150 μg was provided in powder filled capsules with a single dose dry powder inhaler (SDDPI).

Indacaterol 300 μgdrug

Indacaterol 300 μg was provided in powder filled capsules with a single dose dry powder inhaler (SDDPI).

Placebodrug

Placebo to indacaterol was provided in powder filled capsules with a single dose dry powder inhaler (SDDPI).