At a glance

ClinicalIndex Comparison Record

N/ACompleted· 110 enrolled

Drug / intervention

propafenone; flecainide; sotalol; dofetilide +1 moredrug

Likely dose

Not stated in record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00408200

NCT00408200N/ACompleted

Compare CT.gov

A Randomized Trial to Assess the Utility of Empirical Anti-Arrhythmic Drug Therapy to Prevent Atrial Arrhythmia During the 6 Weeks Following Pulmonary Vein Isolation to Treat Paroxysmal Atrial Fibrillation

University of Pennsylvania·interventional·Posted Dec 6, 2006·Updated Mar 7, 2013

In Brief

A clinical study evaluating propafenone; flecainide; sotalol; dofetilide and Radiofrequency catheter ablation for Atrial Fibrillation. Completed, enrolled 110 participants across 2 sites.

Detailed Summary

The purpose of this study is to examine the overall effectiveness of anti-arrhythmic medicines (to control heart rhythm) prescribed after an ablation procedure for atrial fibrillation.

Study Details

Study Typeinterventional

Allocation--

Masking--

Primary Purpose--

ConditionsAtrial Fibrillation

CountriesUnited States

Collaborators--

Timeline

N/ACompletedFinished

200720082009201020112012201320142015201620172018201920202021202220232024202520262027

Enrollment StartNov 2006

First PostedDec 2006

Primary CompletionApr 2008

Study CompletionJun 2008

TodayJul 2026

First PostedDec 6, 2006

Enrollment StartNov 1, 2006

Primary CompletionApr 1, 2008

Study CompletionJun 1, 2008

TodayJul 2, 2026

Enrollment to primary: 1.4 yearsPosted 19.6 years ago

Interventions

propafenone; flecainide; sotalol; dofetilidedrug

Above drugs prescribed per established guidelines for treatment of AF

Radiofrequency catheter ablationdevice

A special catheter that delivers radiofrequency (heat) energy is advanced into the heart and used to destroy small areas of heart tissue responsible for causing atrial fibrillation. All catheters / devices used in the study are FDA approved for human use and currently being used to perform the AF ablation procedure in the United Sates.