CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 142 enrolled
Drug / intervention
Torasemide Prolonged Release +1 moredrug
Likely dose
Torasemide Prolonged Release 10mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00409942
NCT00409942Phase 4Completed
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Prospective, Randomised, Open, Blinded-endpoint Study of Torasemide Prolonged Release vs Furosemide to Evaluate the Efficacy on Myocardial Fibrosis in Patients With Heart Failure

Ferrer Internacional S.A.·interventional·Posted Dec 12, 2006·Updated Jul 15, 2009

In Brief

A Phase 4 clinical trial evaluating Torasemide Prolonged Release and Furosemide for Congestive Heart Failure. Completed, enrolled 142 participants across 23 sites.

Detailed Summary

Torasemide is a loop diuretic (pyridine-sulfonylurea)with a wide experience in the treatment of oedema associated to heart failure, kidney or liver disease and either in the treatment of arterial hypertension (alone or combined with other anti-hypertensive drugs). It has been developed a new formulation of Torasemide (Torasemide prolonged release). The aim of this trial is to study the effects of Torasemide prolonged released in comparison with furosemide, in the reduction of myocardial fibrosis in patients with chronic heart failure (Class II-IV of the New York Heart Association Classification.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCongestive Heart Failure
CountriesSpain
Collaborators--

Timeline

Phase 4CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedDec 12, 2006
Enrollment StartMar 1, 2007
Primary CompletionJun 1, 2009
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 19.6 years ago

Interventions

Torasemide Prolonged Releasedrug

Torasemide Prolonged release 10mg/day up to 40mg/day, treatment duration:8 months

Furosemidedrug

Furosemide 40mg/day up to 160mg/day, Treatment duration:8 months