At a glance
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Parenteral Hydration in Advanced Cancer Patients - A Randomized Controlled Trial
In Brief
A clinical study evaluating Saline for Advanced Cancer and Dehydration. Completed, enrolled 262 participants across 5 sites.
Detailed Summary
The goal of this clinical research study is to learn whether being hydrated (given liquids) through a catheter in a vein or in the tissue under the skin can improve symptoms of dehydration. Objectives: 1.1 Determine whether parenteral hydration is superior to placebo in improving symptoms associated with dehydration (such as fatigue, myoclonus, sedation, and hallucinations) in advanced cancer patients receiving hospice care. 1.2 Determine whether parenteral hydration is superior to placebo in delaying the onset or reducing the severity of delirium in patients with advanced cancer receiving hospice care. 1.3 Describe the meaning patients and primary caregivers attribute to dehydration and re-hydration at the end of patient's lives.
Study Details
Timeline
Interventions
1,000 ml of normal saline (0.9% sodium chloride) parenterally over 4 hours daily.
100 ml of normal saline (0.9% sodium chloride) parenterally over 4 hours daily.