CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 130 enrolled
Drug / intervention
Pine Bark Extract (Flavangenol®)drug
Likely dose
Flavangenol 200 mg orally once daily (4 tablets × 50 mg each)AI-extracted
Key inclusion· 6
  • ✓Systolic blood pressure between 125 and 159 mmHg
  • ✓Diastolic blood pressure < 100 mmHg
  • ✓BMI 25.0–34.9 kg/m²
  • ✓Triglycerides < 450 mg/dL
Key exclusion· 4
  • ✕Diastolic blood pressure > 95 mmHg
  • ✕LDL cholesterol > 170 mg/dL
  • ✕Triglycerides > 300 mg/dL
  • ✕Fasting blood glucose > 110 mg/dL

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00425945
NCT00425945N/ACompleted
CompareCT.gov

Cardiovascular Effects of Pine Bark Extract

Stanford University·interventional·Posted Jan 24, 2007·Updated Apr 2, 2014

In Brief

A clinical study evaluating Pine Bark Extract (Flavangenol®) for Hypertension. Completed, enrolled 130 participants across 1 site.

Detailed Summary

The purpose of this study is to investigate the efficacy of Flavangenol® (Toyo Shinyaku, Japan), a pine bark extract, in lowering blood pressure and improving glycemic control and plasma lipoprotein profile.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHypertension
CountriesUnited States
CollaboratorsFunded by Toyo Shinyaku Co Ltd

Timeline

N/ACompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJan 24, 2007
Enrollment StartOct 1, 2006
Primary CompletionAug 1, 2008
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 19.4 years ago

Interventions

Pine Bark Extract (Flavangenol®)drug

Flavangenol 200 mg per day. Flavangenol is a brand of pine bark extract manufactured by Toyo Shinyaku of Saga, Japan. Dosage delivered as four tablets, each containing 50 mg Flavangenol, all 4 tablets taken once per day orally for 12 weeks.