At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 53 enrolled
Drug / intervention
Ephedrine [Synonyms: Ephedra, Ephedrinum] +1 moredrug
Likely dose
Ephedrine [Synonyms: Ephedra, Ephedrinum] 25 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Double-Blind, Placebo-Controlled Study to Evaluate the Effect of Intramuscular Ephedrine on the Incidence of Perioperative Nausea and Vomiting During Elective Cesarean Section
In Brief
A Phase 2 clinical trial evaluating Ephedrine [Synonyms: Ephedra, Ephedrinum] and Saline Placebo for Nausea and 2 related conditions. Completed, enrolled 53 participants across 1 site.
Detailed Summary
The purpose of this research study is to investigate if the incidence of nausea and vomiting that subjects experience during and after a Cesarean section can be reduced by giving a shot of the drug ephedrine into the thigh muscle at the time of spinal anesthesia administration.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsNausea, Vomiting, Cesarean Section
CountriesUnited States
CollaboratorsNew York Presbyterian Hospital
Timeline
Phase 2CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartFeb 2007
First PostedFeb 2007
Primary CompletionSep 2010
TodayJul 2026
First PostedFeb 9, 2007
Enrollment StartFeb 1, 2007
Primary CompletionSep 1, 2010
TodayJul 2, 2026
Enrollment to primary: 3.6 yearsPosted 19.4 years ago
Interventions
Ephedrine [Synonyms: Ephedra, Ephedrinum]drug
25 mg, IM (in the muscle), one time
Saline Placebodrug
0.5 mL, IM (in the muscle), one time