At a glance
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Assessment of Airway Obstruction in Infants With Lower Respiratory Infections
In Brief
A clinical study evaluating Inhaled primatene will be given as a breathing treatment and Nasal Washing for Bronchiolitis and Respiratory Syncytial Virus Infections. Completed, enrolled 59 participants across 1 site.
Detailed Summary
The purpose of this study is to evaluate how two different aerosol medications may improve airway function in infants with respiratory illness. We are using two different medications and comparing the difference in lung function after each medication. We will also be taking a nasal wash sample for VEGF. We will be using this in comparing how infants respond to the aerosol medications as well. We hope to help standardize medications used for infants with bronchiolitis and RSV.
Study Details
Timeline
Interventions
While the research subject is sedated an inhaled mist of primatene mist will be given to the patient.
1-3 mls of normal saline will be instilled into the infant's nose and then aspirated to obtain the nasal fluid, which will be analyzed for VEGF level by ELISA and viral antigens by immunoflourescence