At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Comparison of Metvix PDT With Its Vehicle in the Treatment of Photoaged Skin
In Brief
A Phase 2 clinical trial evaluating Metvix Cream 160 mg/g and Metvix Vehicle Group for Photoaged Skin. Completed, enrolled 32 participants across 3 sites in 2 countries.
Detailed Summary
Skin photoaging or skin photodamage were terms used to describe the change in the structure, function and appearance of skin caused by prolonged and repeated exposure to sunlight or other ultraviolet light sources. The visible effects of skin photodamage were fine lines, skin sagging, skin roughness, liver spots and also the appearance of red patches made up of thin red vessels (called telangiectasia). More and more people were presenting to doctors with concerns about skin photodamage and the demand for corrective procedures was increasing. Metvix photodynamic therapy (Metvix PDT) is a procedure currently marketed in several countries in Europe (including the United Kingdom \[UK\] and Spain) and in Australia, for the treatment of benign forms of skin cancer (example, actinic keratosis). The aim of the study was to assess whether Metvix PDT would be effective in correcting the effects related to photodamage and whether it would be well tolerated.
Study Details
Timeline
Interventions
Participants were treated with topical administration of Metvix cream.
Participants were treated with topical administration of Metvix Vehicle cream.