CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 219 enrolled
Drug / intervention
C. propionate - Corticosteroid 1 +5 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00438399
NCT00438399Phase 3Completed

Subject Preference Comparison Between Clobetasol Propionate Shampoo, 0.05% and Three Other Topical Corticosteroids in the Treatment of Moderate to Severe Scalp Psoriasis

Galderma R&D·interventional·Posted Feb 22, 2007·Updated Feb 18, 2021

In Brief

A Phase 3 clinical trial evaluating C. propionate - Corticosteroid 1, C. propionate- Corticosteroid 2, and 4 other interventions for Scalp Psoriasis. Completed, enrolled 219 participants across 1 site.

Detailed Summary

The scalp is one of the most common affected sites in psoriatic patients as 79% of them have scalp involvement.It has also a psychological aspect with 31% of patients with scalp psoriasis indicating distress. Topical agents remain the mainstay of treatment for scalp psoriasis. However, they are not always ideal because they might be inconvenient and messy to use, stain or damage hair. The test shampoo, Clobetasol propionate Shampoo 0.05% (marketed in the USA under the tradename of Clobex®) was developed to provide the strongest available corticosteroid as a short-contact therapy in order to improve the chances of it being effective and reduce the potential for traditional side-effects. The objective of this study is to compare subject's overall preference between Clobetasol propionate shampoo 0.05% and three other topical corticosteroids in the treatment of moderate to severe scalp psoriasis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsScalp Psoriasis
CountriesItaly
Collaborators--

Timeline

Phase 3CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedFeb 22, 2007
Enrollment StartFeb 1, 2007
Primary CompletionJan 1, 2008
Study CompletionFeb 1, 2008
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 19.4 years ago

Interventions

C. propionate - Corticosteroid 1drug

Twice daily application

C. propionate- Corticosteroid 2drug

Twice daily application

C. propionate -Corticosteroid 3drug

Twice daily application

Corticosteroid 1- C. propionatedrug

Twice daily application

Corticosteroid 2 - C. propionatedrug

Twice daily application

Corticosteroid 3 - C. propionatedrug

Twice daily application