CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 1,068 enrolled
Drug / intervention
Telcagepant 300 mg soft gel capsules +5 moredrug
Likely dose
Telcagepant 300 mg soft gel capsulesfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00443209
NCT00443209Phase 3Completed
CompareCT.gov

A Multicenter, Double-Blind, Active-Controlled, Parallel Group Study to Examine the Safety, Tolerability and Efficacy of Oral MK-0974 for the Long Term Treatment of Acute Migraine With or Without Aura

Merck Sharp & Dohme LLC·interventional·Posted Mar 5, 2007·Updated Oct 17, 2018

In Brief

A Phase 3 clinical trial evaluating Telcagepant 300 mg soft gel capsules, Telcagepant 280 mg tablets, and 4 other interventions for Migraine. Completed, enrolled 1,068 participants.

Detailed Summary

The purpose of this study is to investigate the safety and tolerability of telcagepant (MK-0974) in the long-term treatment of acute migraine in adult participants. The primary hypothesis of this study is that telcagepant is well tolerated in the long-term treatment of acute migraine in adult participants.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMigraine
Countries--
Collaborators--

Timeline

Phase 3CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMar 5, 2007
Enrollment StartFeb 21, 2007
Primary CompletionJan 22, 2009
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 19.3 years ago

Interventions

Telcagepant 300 mg soft gel capsulesdrug

One capsule taken orally at onset of migraine

Telcagepant 280 mg tabletsdrug

One tablet taken orally at onset of migraine

Rizatriptan 10 mg tabletsdrug

One tablet taken orally at onset of migraine

Placebo to telcagepant capsulesdrug

One capsule taken orally at onset of migraine

Placebo to telcagepant tabletsdrug

One tablet taken orally at onset of migraine

Placebo to rizatriptan tabletsdrug

One tablet taken orally at onset of migraine