At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Trial of Early Aggressive Therapy in Juvenile Idiopathic Arthritis (TREAT in JIA)
In Brief
A Phase 4 clinical trial evaluating methotrexate and methotrexate - etanercept - prednisolone arm for Juvenile Chronic Polyarthritis and 2 related conditions. Completed, enrolled 85 participants across 15 sites.
Detailed Summary
The purpose of this study is to compare two aggressive drug regimens for children with poly-juvenile idiopathic arthritis (JIA) and extended oligo JIA.
Study Details
Timeline
Interventions
Methotrexate 0.5 mg/kg given by sub cutaneous injection once per week, plus placebo etanercept and and placebo prednisolone
methotrexate 0.5 mg/kg given by sub cutaneous injection once per week, plus etanercept 0.8 mg/kg given by sub cutaneous injection once per week, plus prednisolone, by mouth daily with decreasing dose tapered over 16 weeks.