CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 247 enrolled
Drug / intervention
RotaTeq® +1 morebiological
Likely dose
RotaTeq® 2 mLfrom record
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Search/NCT00443846
NCT00443846Phase 3Completed

An Open-label, Randomised, Comparative, Multi-centre Study of the Immunogenicity and Safety of the Concomitant Use of a Live Pentavalent Rotavirus Vaccine (RotaTeq®) and a Meningococcal Group C Conjugate (MCC) Vaccine in Healthy Infants

Merck Sharp & Dohme LLC·interventional·Posted Mar 6, 2007·Updated Jun 20, 2018

In Brief

A Phase 3 clinical trial evaluating RotaTeq® and NeisVac-C® for Meningitis, Meningococcal and Rotavirus Infections. Completed, enrolled 247 participants.

Detailed Summary

Primary objective: To check if RotaTeq® can be administered concomitantly with meningococcal Group C vaccine without impairing the efficacy of MCC vaccine. The hypothesis tested is that the seroprotection rate for MMC at 28 days after the second MCC vaccination with concomitant administration of RotaTeq® is non-inferior to that without non-concomitant (sequential) administration of RotaTeq®.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
Countries--
Collaborators--

Timeline

Phase 3CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMar 6, 2007
Enrollment StartFeb 13, 2007
Primary CompletionSep 4, 2007
Study CompletionOct 23, 2007
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 19.3 years ago

Interventions

RotaTeq®biological

Rotavirus vaccine, live, oral, pentavalent, 2 mL solution for oral administration.

NeisVac-C®biological

Meningiococcal Group C Polysaccharide Conjugate Vaccine Absorbed, 0.5 mL suspension for intramuscular injection.