CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 52 enrolled
Drug / intervention
lapatinib +1 moredrug
Likely dose
lapatinib 1500 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00444535
NCT00444535Phase 2Completed

A Phase II, Open-Label Study of the Clinical Activity, Safety, and Tolerability of Lapatinib in Combination With Bevacizumab in Subjects With Advanced or Metastatic ErbB2-Overexpressing Breast Cancer

Novartis Pharmaceuticals·interventional·Posted Mar 8, 2007·Updated Oct 25, 2021

In Brief

A Phase 2 clinical trial evaluating lapatinib and bevacizumab for Neoplasms, Breast. Completed, enrolled 52 participants across 9 sites.

Detailed Summary

This study will examine the efficacy and safety of lapatinib and bevacizumab in patients with ErbB2-overexpressing breast cancer.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMar 8, 2007
Enrollment StartFeb 27, 2007
Primary CompletionJul 22, 2008
Study CompletionJun 19, 2020
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 19.3 years ago

Interventions

lapatinibdrug

1500 mg oral lapatinib (once daily)

bevacizumabdrug

10 mg/kg intravenous bevacizumab (every two weeks)