CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 906 enrolled
Drug / intervention
Ibuprofen/famotidine +1 moredrug
Likely dose
Ibuprofen/famotidine 26.6mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00450216
NCT00450216Phase 3Completed

A Randomized, Double-Blind, Phase 3 Study of the Efficacy and Safety of HZT-501 in Subjects Requiring NSAID Treatment

Amgen·interventional·Posted Mar 22, 2007·Updated Dec 16, 2024

In Brief

A Phase 3 clinical trial evaluating Ibuprofen/famotidine and Ibuprofen for Ulcer. Completed, enrolled 906 participants.

Detailed Summary

The purpose of this study is to evaluate whether HZT-501 is effective in reducing the rate of development of ibuprofen-associated ulcers in patients who require long-term daily use of ibuprofen.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsUlcer
Countries--
Collaborators--

Timeline

Phase 3CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMar 22, 2007
Enrollment StartMar 1, 2007
Primary CompletionAug 1, 2008
Study CompletionOct 1, 2008
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 19.3 years ago

Interventions

Ibuprofen/famotidinedrug

HZT-501: Ibuprofen800mg/famotidine 26.6mg administered orally 3 times daily for 24 weeks

Ibuprofendrug

Ibuprofen 800mg administered orally 3 times daily for 24 weeks