CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted
Drug / intervention
Blood AM, IL-6, ACTH, Cortisol, Glucose and Insulinprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00459511
NCT00459511N/ACompleted
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The Importance of Adrenomedullin (AM) on Pituitary-Adrenal Axis and Glucose Kinetics in Pediatric Patients With Systemic Inflammatory Response Syndrome

University of Sao Paulo·observational·Posted Apr 12, 2007·Updated Apr 12, 2007

In Brief

An observational study evaluating Blood AM, IL-6, ACTH, Cortisol, Glucose and Insulin for Systemic Inflammatory Response Syndrome and Hyperglycemia. Completed, across 1 site.

Detailed Summary

Hyperglycemia is frequent manifestations of the human metabolic response to systemic inflammatory response syndrome (SIRS),sepsis and septic shock, and are implicated in the clinical outcome. Adrenomedullin is elevated in SIRS, sepsis and septic shock and has been demonstrated the inhibitory role on insulin and adrenocorticotropic hormone secretion. Our hypothesis is that: AM elevation after SIRS could be the responsible to maintain hyperglycemia

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsSystemic Inflammatory Response Syndrome, Hyperglycemia
CountriesBrazil
CollaboratorsCoordenação de Aperfeiçoamento de Pessoal de Nível Superior.

Timeline

N/ACompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedApr 12, 2007
Enrollment StartJan 1, 2006
Study CompletionOct 1, 2006
TodayJul 2, 2026
Posted 19.2 years ago

Interventions

Blood AM, IL-6, ACTH, Cortisol, Glucose and Insulinprocedure