CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 102 enrolled
Drug / intervention
5 days of IV antibiotics (ceftriaxone and metronidazole) +1 moredrug
Likely dose
Home with oral antibiotics when eating (ampicillin/clavulanic acid) 40mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00462020
NCT00462020N/ACompleted
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Intravenous Versus Intravenous/Oral Antibiotics for Perforated Appendicitis

Children's Mercy Hospital Kansas City·interventional·Posted Apr 18, 2007·Updated Feb 21, 2021

In Brief

A clinical study evaluating 5 days of IV antibiotics (ceftriaxone and metronidazole) and Home with oral antibiotics when eating (ampicillin/clavulanic acid) for Perforated Appendicitis. Completed, enrolled 102 participants across 1 site.

Detailed Summary

The objective of this study is to scientifically evaluate two different management strategies for perforated appendicitis. The hypothesis is that early discharge with oral antibiotic therapy may result in a dramatic decrease in medical care expenses for the patient. The primary outcome variable between the two strategies is abscess rate.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPerforated Appendicitis
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedApr 18, 2007
Enrollment StartMar 1, 2007
Primary CompletionNov 1, 2008
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 19.2 years ago

Interventions

5 days of IV antibiotics (ceftriaxone and metronidazole)drug

5 days of IV antibiotics (ceftriaxone and metronidazole once a day dosing)

Home with oral antibiotics when eating (ampicillin/clavulanic acid)drug

Augmentin 40mg/kg BID when tolerating POs to complete 7 days total