At a glance
ClinicalIndex Comparison RecordN/ACompleted· 159 enrolled
Drug / intervention
Ibuprofen +2 moredrug
Likely dose
Ibuprofen 400 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
COX Inhibition & Musculoskeletal Responses to Exercise
In Brief
A clinical study evaluating Ibuprofen, Placebo, and 1 other intervention for Aging and Physical Fitness. Completed, enrolled 159 participants across 1 site.
Detailed Summary
The purpose of this study is to determine if the use of ibuprofen blocks the benefits of exercise to build bone and muscle mass.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAging, Physical Fitness
CountriesUnited States
CollaboratorsNational Institute on Aging (NIA)
Timeline
N/ACompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedApr 2007
Enrollment StartJul 2007
Primary CompletionDec 2011
TodayJul 2026
First PostedApr 19, 2007
Enrollment StartJul 1, 2007
Primary CompletionDec 1, 2011
TodayJul 2, 2026
Enrollment to primary: 4.4 yearsPosted 19.2 years ago
Interventions
Ibuprofendrug
400 mg with each exercise session (up to 5 days per week) for 9 months
Placebodrug
with each exercise session (up to 5 days per week) for 9 months
musculoskeletal-loading exercisebehavioral
Exercise training program designed to increase bone and muscle mass, including weight lifting and weight-bearing exercises such as jumping in place and treadmill walking up to 5 days per week for 9 months