At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 3 enrolled
Drug / intervention
NucleomaxX (contains uridine)drug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Uridine Supplementation, Mitochondrial Function, and Glucose Metabolism in HIV
National Center for Complementary and Integrative Health (NCCIH)·interventional·Posted May 10, 2007·Updated May 16, 2012
In Brief
A Phase 2 clinical trial evaluating NucleomaxX (contains uridine) for HIV Infections and 2 related conditions. Completed, enrolled 3 participants across 1 site.
Detailed Summary
The purpose of this study is to determine whether uridine supplementation will improve insulin sensitivity and overall carbohydrate metabolism in HIV-positive subjects who are currently undergoing treatment with antiretroviral regimens containing stavudine or zidovudine and who have evidence of impaired mitochondrial function and insulin resistance.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHIV Infections, Insulin Resistance, Hyperlactatemia
CountriesUnited States
Collaborators--
Timeline
Phase 2CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartApr 2007
First PostedMay 2007
Primary CompletionJan 2012
TodayJul 2026
First PostedMay 10, 2007
Enrollment StartApr 1, 2007
Primary CompletionJan 1, 2012
TodayJul 2, 2026
Enrollment to primary: 4.8 yearsPosted 19.1 years ago
Interventions
NucleomaxX (contains uridine)drug
Escalated doses of NucleomaxX tid