At a glance
ClinicalIndex Comparison Record- ✓Elective thyroid or combined thyroid/parathyroid surgery limited to central cervical compartment
- ✓Informed consent required
- ✕Intolerance to bupivacaine or saline
- ✕Recurrent thyroid or parathyroid disease
- ✕Neck dissection or sternotomy procedures
- ✕Emergency surgery
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Impact and Cost Efficiency of Bilateral, Superficial Cervical Block in Thyroid Surgery Under General Anesthesia
In Brief
A Phase 3 clinical trial evaluating bilateral superficial cervical block and placebo bilateral superficial cervical block for Thyroidectomy. Completed, enrolled 183 participants across 1 site.
Detailed Summary
The study investigates the impact on post-operative pain of the superficial cervical block with bupivacaine combined with subcutaneous infiltration of the incisional area in thyroid surgery under general anesthesia. In addition, cost savings using the cervical block are evaluated (due to reduced length of hospital stay). The study is prospective, randomized, double blind, and placebo-controlled. The study is performed at the Department of Surgery, Cantonal Hospital of St. Gallen.
Study Details
Timeline
Interventions
10 ml of 5% bupivacaine (Carbostesin®) was used for each side. Along the cranial dorsal edge of the sternocleidomastoid muscle, three deposits of approximately 2.5 ml were injected to anaesthetize the cervical plexus with its nervus transversus colli. To anaesthetize the region of the planned skin incision, the remaining 2·5 ml was injected subcutaneously on each side.
10 ml of saline (the carrier of bupivacaine in the experimental treatment) was used for each side. Along the cranial dorsal edge of the sternocleidomastoid muscle, three deposits of approximately 2.5 ml were injected to anaesthetize the cervical plexus with its nervus transversus colli. To anaesthetize the region of the planned skin incision, the remaining 2·5 ml was injected subcutaneously on each side.