At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Performance of Cimetidine-corrected MDRD Equation in Renal Transplant Patients
In Brief
A clinical study evaluating cimetidine arrow for Kidney Transplantation. Completed, enrolled 59 participants across 1 site.
Detailed Summary
Among the different creatinine-based GFR predicting equations, the MDRD equation gives the best prediction in renal transplantation but does not provide the level of accuracy usually seen in renal patients with native kidneys. Blocking the tubular secretion of creatinine with an oral administration of cimetidine is likely to make creatinine a more accurate marker of GFR. We will test the hypothesis that the accuracy of the MDRD equation will be improved in renal transplant patients by incorporating into the equation a cimetidine-corrected serum creatinine value.
Study Details
Timeline
Interventions
patients who received cimétidine