At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 360 enrolled
Drug / intervention
EpiCept-NP-1 Cream +2 moredrug
Likely dose
Gabapentin Capsules 1800mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Phase II, Double-Blind, Randomized, Placebo-Controlled Non-inferiority Trial of EpiCept™ NP-1 Topical Cream (2% Ketamine / 4% Amitriptyline) vs. Oral Gabapentin in Postherpetic Neuralgia (PHN)
In Brief
A Phase 2 clinical trial evaluating EpiCept-NP-1 Cream, Gabapentin Capsules, and 1 other intervention for Post Herpetic Neuralgia and 3 related conditions. Completed, enrolled 360 participants across 1 site.
Detailed Summary
The purpose of this study is to compare EpiCept™ NP-1 Topical Cream (2% ketamine / 4% amitriptyline) vs. Oral Gabapentin in the treatment of Postherpetic Neuralgia (PHN)
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPost Herpetic Neuralgia, PHN, Neuropathy, Nerve Pain
CountriesIndia
Collaborators--
Timeline
Phase 2CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMay 2007
Enrollment StartJul 2007
Primary CompletionJun 2008
TodayJul 2026
First PostedMay 21, 2007
Enrollment StartJul 1, 2007
Primary CompletionJun 1, 2008
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 19.1 years ago
Interventions
EpiCept-NP-1 Creamdrug
ketamine 4% amitriptyline 2% cream, twice daily for 4 weeks
Gabapentin Capsulesdrug
1800mg/day capsules for 4 weeks
placebodrug
placebo cream and caps