CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 36 enrolled
Drug / intervention
Probiotic or placebo yogurt consumed daily +3 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00480129
NCT00480129Phase 1Completed

The Anti-allergic Effects of Specific Probiotics - a Double Blind Clinical Study

In Brief

A Phase 1 clinical trial evaluating Probiotic or placebo yogurt consumed daily, Mini Rhinoconjunctivitis Quality of Life Questionnaire, and 2 other interventions for Allergic Rhinitis. Completed, enrolled 36 participants across 1 site.

Detailed Summary

We hypothesize that specifically selected probiotics can alleviate symptoms of allergy in lactose tolerant individuals. Two strains of probiotics, Lactobacillus rhamnosus GR-1, and Bifidobacterium adolescentis 7007-05 will be used to create a yogurt product. Additionally a non-probiotic yogurt product will also be made as a placebo. Allergy sufferers will be asked to consume one of the two types of yogurts (blinded) for two months. During the two months there will be 3 sampling days, for blood samples and nasal lavage samples. Additionally Mini Rhinoconjunctivitis Quality of Life Questionnaires will be filled out weekly over the two months. After the two months of perceived responses as well sample analysis we should have a better idea of how these specific probiotic effect the immune system and allergies.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada

Timeline

Phase 1CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMay 30, 2007
Enrollment StartMay 1, 2007
Primary CompletionSep 1, 2007
Study CompletionOct 1, 2007
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 19.1 years ago

Interventions

Probiotic or placebo yogurt consumed dailybehavioral

Mini Rhinoconjunctivitis Quality of Life Questionnairedevice

Blood sampleprocedure

Nasal lavageprocedure