At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
The Effect of Dexamethasone on Symptoms in Patients With Advanced Cancer
In Brief
A Phase 2 clinical trial evaluating Dexamethasone and Placebo for Solid Tumors. Active but no longer recruiting, targeting 132 participants across 2 sites.
Signals
Detailed Summary
The goal of this clinical research study is to learn if dexamethasone can help to control symptoms such as fatigue, pain, nausea, weight loss, loss of appetite, sleep problems, and/or depression in patients with advanced cancer.
Study Details
Timeline
Arms & Interventions
Dexamethasone 4 mg orally two times a day for 14 days. On day 15 \[ ± 3 days\], all patients receive dexamethasone 4 mg orally twice a day for 7 days, and then the dose of dexamethasone tapered to 2 mg orally twice a day between days 22 to 28.
Placebo by mouth (PO) twice daily for 14 days. On day 15 \[ ± 3 days\], all patients receive dexamethasone 4 mg orally twice a day for 7 days, and then the dose of dexamethasone tapered to 2 mg orally twice a day between days 22 to 28.
Interventions
4 mg PO (by mouth) twice daily x 14 days
Placebo PO twice daily x 14 days