At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Randomized Trial of Pelvic Irradiation With or Without Concurrent Weekly Cisplatin in Patients With Pelvic-Only Recurrence of Carcinoma of the Uterine Corpus
In Brief
A Phase 2 clinical trial evaluating 3-Dimensional Conformal Radiation Therapy, Cisplatin, and 2 other interventions for Endometrial Endometrioid Adenocarcinoma, Variant With Squamous Differentiation and 7 related conditions. Targeting 165 participants across 441 sites in 2 countries.
Detailed Summary
This randomized phase II trial studies radiation therapy and cisplatin to see how well they work compared with radiation therapy alone in treating patients with endometrial cancer that has come back. Radiation therapy uses high-energy x-rays and other types of radiation to kill tumor cells. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known whether giving radiation therapy together with cisplatin is more effective than radiation therapy alone in treating patients with endometrial cancer.
Study Details
Timeline
Interventions
Undergo 3-dimensional conformal radiation therapy
Given IV
Undergo IMRT
Given intracavitarily or interstitially