At a glance
ClinicalIndex Comparison RecordPhase 3Completed· 63 enrolled
Drug / intervention
Nicotinic acid +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Niacin (as a Vasodilator), and a Topical Steroid (for Macular Edema), Non-Ischemic CRVO,HRVO,BRVO
In Brief
A Phase 3 clinical trial evaluating Nicotinic acid and Prednisolone acetate for Retinal Vein Occlusion. Completed, enrolled 63 participants across 1 site.
Detailed Summary
The purpose of this study is to determine whether Niacin, a B vitamin, may act as a vasodilator to encourage earlier formation of collateral blood vessels that may serve to bypass the obstructed vein in the eye. The topical steroid eye drops are aimed at reducing swelling in the retina, until the collateral vessels have a chance to develop.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRetinal Vein Occlusion
CountriesUnited States
Collaborators--
Timeline
Phase 3CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartOct 2006
First PostedJun 2007
Primary CompletionOct 2016
TodayJul 2026
First PostedJun 27, 2007
Enrollment StartOct 1, 2006
Primary CompletionOct 1, 2016
TodayJul 2, 2026
Enrollment to primary: 10 yearsPosted 19.0 years ago
Interventions
Nicotinic aciddrug
topical eye drops
Prednisolone acetatedrug
topical eye drops