At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 30 enrolled
Drug / intervention
Hemospan (MP4OX) +1 moredrug
Likely dose
Hemospan (MP4OX) 1000 mLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Clinical Safety (Phase Ib/II) Increasing Dose Study of MP4 (Hemospan) in Orthopedic Surgery Patients
In Brief
A Phase 2 clinical trial evaluating Hemospan (MP4OX) and Ringer's lactate for Hypotension and Hypoxia. Completed, enrolled 30 participants across 2 sites.
Detailed Summary
The purpose of this study is to evaluate the safety and possible effectiveness of Hemospan solution in patients undergoing elective orthopedic surgery who receive spinal anesthesia.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHypotension, Hypoxia
CountriesSweden
Collaborators--
Timeline
Phase 2CompletedFinished
2003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartApr 2003
Primary CompletionJul 2006
Study CompletionAug 2006
First PostedJul 2007
TodayJul 2026
First PostedJul 2, 2007
Enrollment StartApr 1, 2003
Primary CompletionJul 1, 2006
Study CompletionAug 1, 2006
TodayJul 2, 2026
Enrollment to primary: 3.3 yearsPosted 19 years ago
Interventions
Hemospan (MP4OX)drug
200, 400, 600, 750, or 1000 mL of Hemospan (MP4OX)
Ringer's lactatedrug
200, 400, 600, 750, or 1000 mL of Ringer's lactate solution