At a glance
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The Natural History of Community-Associated Methicillin-Resistant Staphylococcus Aureus (CA-MRSA) Infections and an Evaluation of Decolonization Strategies
In Brief
A clinical study evaluating Mupirocin ointment, Chlorhexidine showers, and 2 other interventions for Abscesses and 3 related conditions. Completed, enrolled 300 participants across 2 sites.
Detailed Summary
The purpose of this study is to determine the natural history of community-associated Staphylococcus aureus infections in both adult and pediatric patients by monitoring the rate of recurrent infections in those colonized with S. aureus. In addition, this study will evaluate the efficiency of commonly prescribed decolonization measures in patients presenting with S. aureus skin and soft tissue infections.
Study Details
Timeline
Interventions
Add a small amount of Mupirocin to the cotton end of a swab. Swab in inner nostril, then repeat in other nostril using new cotton swab with ointment. Twice daily treatment for 5 days.
Apply Clorhexidine wash to entire body once daily for 5 days.
Pour 2 ounces of bleach into water-filled bath tub. Soak in bath for 15 minutes. Apply once daily for 5 days.
Repeat hygiene methods for 5 days.