CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 8 enrolled
Drug / intervention
sargramostim +4 morebiological
Likely dose
sargramostim 250 μgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00514215
NCT00514215Phase 2Completed

Percutaneous Cryotherapy and Aerosolized GM-CSF for Pulmonary Metastases and Primary Lung Cancer

Barbara Ann Karmanos Cancer Institute·interventional·Posted Aug 9, 2007·Updated Mar 5, 2020

In Brief

A Phase 2 clinical trial evaluating sargramostim, flow cytometry, and 3 other interventions for Kidney Cancer and 3 related conditions. Completed, enrolled 8 participants across 1 site.

Detailed Summary

RATIONALE: Cryotherapy kills tumor cells by freezing them. Giving an injection of GM-CSF before cryotherapy and inhaling GM-CSF after cryotherapy may interfere with the growth of tumor cells and shrink the tumor. Giving cryotherapy together with GM-CSF may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving cryotherapy together with GM-CSF works in treating patients with lung metastases or primary lung cancer.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2CompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedAug 9, 2007
Enrollment StartJan 1, 2006
Primary CompletionMar 1, 2010
TodayJul 2, 2026
Enrollment to primary: 4.2 yearsPosted 18.9 years ago

Interventions

sargramostimbiological

250 μg, inhaled, two times a day, on days 4-10 and days 36-42

flow cytometryother

Days 1 \& 32

immunoenzyme techniqueother

Days 1 \& 32

biopsyprocedure

CT guided biopsy on days 1 \& 32

cryosurgeryprocedure

Days 1 and 32