CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 1,439 enrolled
Drug / intervention
Hyperinsulinemic-normoglycemic clamp +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00524472
NCT00524472N/ACompleted
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The Effect of Hyperinsulinemic Glucose Control on Outcomes Following Cardiac Surgery

The Cleveland Clinic·interventional·Posted Sep 3, 2007·Updated Oct 26, 2018

In Brief

A clinical study evaluating Hyperinsulinemic-normoglycemic clamp and insulin at the standard of care levels for Cardiac Surgery. Completed, enrolled 1,439 participants across 2 sites in 2 countries.

Detailed Summary

Patients undergoing cardiac surgery will be randomized into one of two groups. Group A will be administered insulin using the hyperinsulinemic-normoglycemic clamp to normalize blood glucose levels intra-operatively. Group B will be administered insulin at the standard of care levels established by the participating institution. Patients will be followed at 10 days, 15 days and one year post-operatively.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCardiac Surgery
CountriesCanada, United States
Collaborators--

Timeline

N/ACompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 3, 2007
Enrollment StartJul 1, 2007
Primary CompletionApr 1, 2015
TodayJul 2, 2026
Enrollment to primary: 7.8 yearsPosted 18.8 years ago

Interventions

Hyperinsulinemic-normoglycemic clampother

Patients will be randomized to receive the hyperinsulinemic-normoglycemic clamp titrating the blood glucose to 80-110 mg/dL.

insulin at the standard of care levelsother

Subjects will be administered insulin at the standard of care levels established by the participating institution.