At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
General Anesthesia Versus Spinal Anesthesia Combined With Intrathecal Morphine in Abdominal Hysterectomy for Benign Gynecological Diseases. A Randomized Open Controlled Study.
In Brief
A Phase 4 clinical trial evaluating Bupivacain, Morphine, and 3 other interventions for Hysterectomy (MeSH nr: E04.950.300.399). Completed, enrolled 180 participants across 5 sites.
Detailed Summary
The purpose of this study is to determine whether spinal anesthesia combined with intrathecal morphine in abdominal hysterectomy on benign gynecological indications gives better outcome concerning duration of hospital stay and postoperative patient comfort than general anesthesia.
Study Details
Timeline
Interventions
5 mg/mL, 4 mL intrathecally as a single dos
0.4 mg/mL; 0.5 mL intrathecally as a single dosage
2-5 mg/kg body weight/hours IV (intravenously) for sedation during the surgery
Induction of anesthesia with 1-2 mg/kg body weight IV (intravenously). After intubation maintenance dosage of 6-10 mg/kg/hour IV during the surgery
100-200 microgram IV (intravenously) at start of anesthesia. 50-100 microgram IV on demand during surgery.
0.6 mg/kg body weight IV (intravenously) at induction of anesthesia. If additional muscle relaxation is needed during surgery 5-10 mg is injected IV. The drug is given only at induction of anesthesia and during surgery
5 mg is given IV (intravenously) before end of surgery